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Toggle ContentCannabiniods are primary components of cannabis, they are more commonly known as CBD,CBA,CBG,CBN,CBC,THC

Many health conditions, both severe and not, are treated with pharmaceutical drugs.  Unfortunately many of these drugs have unpleasant or dangerous side effects. In some instances, Cannabiniods may offer non-toxic, natural benefits for individuals who want to avoid or reduce the number of pharmaceuticals they are taking

The human body naturally produces Cannabiniods

Phytocannabinoids are cannabinoids derived from plants. Endocannabinoids are cannabinoids produced naturally in the human body.

One example of an endocannabinoid is anandamide, or ‘the bliss molecule.’ This molecule activates the CB1 receptor.

Benefits of activating the CB1 receptor include:

  • Relieving depression 
  • Increasing myelin formation 
  • Lowering intestinal inflammation 
  • Decreasing intestinal permeability (Leaky Gut Syndrome) 
  • Lowering blood pressure 
  • Lowering anxiety 
  • Reducing fear and paranoia 
  • Increasing BDNF levels 
  • Increasing PPARy expression 
  • Reducing GPR55 signaling 
  • Lowering prolactin

An enzyme in the body known as FAAH is responsible for breaking down anandamide. Cannabiniods are an inhibitor of FAAH, meaning more anandamide to be available to the CB1 receptors.

Anandamide has been shown to stop the proliferation of breast cancer cells, promote anti-anxiety and antidepressant effects, and increases neurogenesis.  Anandamide plays a role in memory and forgetting, creating a potential natural value for individuals with post traumatic stress disorder (PTSD).

Cannabiniods effect severeal Neurotransmitter Receptors

Cannabiniods are an allosteric modulator at several receptor sites in our bodies.

Allosteric modulators change the shape of specific receptors to alter their ability to interact with neurotransmitters.

Cannabiniods are a positive allosteric modulator of the mu and delta opioid receptors. This means it enhances the ability of these receptors to receive endogenous enkephalins which can increase quality of life and naturally reduce pain.  

Cannabiniods activate the 5-ht1A receptor. The 5-ht1A receptor helps regulate anxiety, addiction, appetite, sleep, pain perception, nausea, and vomiting. 

Cannabiniods also antagonizes GPR55 receptors. GPR55 receptors are widely distributed in the brain (especially the cerebellum) and help to control bone density and blood pressure.

When activated, GPR55 promotes cancer cell proliferation. This antagonizing action may help explain the natural value of supplementing with Cannabiniods in individuals with cancer, osteoporosis, and high blood pressure. [S]

Cannabiniods activate TRPV1 receptors. TRPV1 is involved in regulating pain, body temperature, and inflammation. Other substances targeting TRPV1 receptors include anandamide, AM404 (a metabolite of acetaminophen), capsaicin, and various cannabinoids such as CBN, CBG, CBA, CBC, THCV, and CBDV.

Lastly, cannabiniods activate PPAR-gamma receptors. PPAR-gamma receptors are located on the cell’s nuclei and play a role in lipid uptake, insulin sensitivity, dopamine release and the degradation of beta-amyloid plaque. This is why Cannabiniods have been found to have natural value for individuals with diabetes, schizophrenia, and Alzheimer’s disease. 

Cannabiniods may help children with seizures and epilepsy 

Perhaps one of the most exciting applications of Cannabiniods is the potential impact for adults and children with epilepsy.

Individuals who were experiencing dozens of seizures daily have found that Cannabiniods can dramatically decrease the these numbers.

Considering the shocking increase in children receiving prescriptions for various ailments, Cannabiniods may provide a non-toxic more natural alternative to pharmaceutical treatments, preventing children from experiencing long term damage or side effects.

The statements regarding these products have not been evaluated by the FSA/MHRA. These products are not intended to diagnose, treat, cure or prevent any disease. These products are not intended for persons under the age of 18.  Please consult your health care professional before starting a new dietary supplement. 

Store in a cool, dry place away from direct sunlight and shake well before each use

TranquiLeaf contains only five ingredients, Vegetable Glycerin, Propylene Glycol, Cannabis Sativa Extract, CBD Extract and Natural Flavours. Nothing else is added guaranteed..

No but we recommend using within two years of opening

Absolutely, you can mix it with any type of vape liquid however this will dilute the strength of the cannabiniods

Vaping TranquiLeaf is not the same as regular E liquid which normally contains nicotine to replace smoking cigarettes. TranquiLeaf contains Zero nicotine, you do not need to be a smoker to vape it. Vaping TranquiLeaf is an effective way of delivering cannabiniods in a controlled manner

TranquiLeaf’s blend of cannabiniods are carried in Vegetable Glycerin & Propylene Glycol which enables it to be vaped. Yes this is what regular vape liquid is made from, however VG & PG are used in various food products as well as regular vape liquid. TranquiLeaf contains zero nicotine, which is what makes regular vape liquid toxic to swallow

This depends on how often you use it, to make the most of your liquid we recommend vaping it in a regular Mouth to Lung style of vape tank with a coil resistance of 1.0ohm – 1.8ohm this will make your liquid burn slower.  Using a sub ohm coil, where the coil has a resitance below 1.0ohm with a  Direct to Lung style of tank (where the user blows huge clouds from there vape)  will vaporize your liquid much faster, a bottle of TranquiLeaf could easily last 4-6 weeks used daily  in moderation and with a Mouth to Lung style vape tank

Should you have anymore questions that are not listed, please do not hesitate to contact us anytime 🙂

For more info on Mouth to lung & Direct to lung, Read this


The statements regarding these products have not been evaluated by the FSA/MHRA. These products are not intended to diagnose, treat, cure or prevent any disease. These products are not intended for persons under the age of 18.  Please consult your health care professional before starting a new dietary supplement.